产品货号:
Z10060
中文名称:
ABCG1抗体
英文名称:
Anti-ABCG1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ABCG1 Antibody |
指标别名 | ABC8;ABCG1;White protein homolog;WHITE1;WHT1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | ABCG1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ABCG1(627-647aa ETCHFQKSEAILRELDVENAK),identical to the related rat and mouse sequences. |
实际分子量 | 75KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | ABCG1(Atp-binding cassette,subfamily g,member 1) also known as ABC8,ABC TRANSPORTER 8 or WHITE,DROSOPHILA,HOMOLOG OF,is a protein that in humans is encoded by the ABCG1 gene.ABCG1 is a regulator of macrophage cholesterol and phospholipid transport.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters.The ABCG1 gene is mapped on 21q22.3.This protein is a member of the White subfamily.It is involved in macrophage cholesterol and phospholipids transport,and may regulate cellular lipid homeostasis in other cell types.ABCG1 is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein.Inhibition of ABCG1 protein expression using an antisense strategy resulted in reduced HDL3-dependent efflux of cholesterol and choline-phospholipids.In macrophages,silencing of GPS2 by RNA interference reduced ABCG1 expression and diminished ABCG1-mediated cholesterol efflux. |
Uniprot ID | P45844 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | ATP-binding cassette,sub-family G(WHITE),member 1 |
蛋白名全称 | ATP-binding cassette sub-family G member 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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